Elemental step thermodynamics of various analogues of indazolium alkaloids to obtaining hydride in acetonitrile-Reference-Cited by-同舟云学术

Elemental step thermodynamics of various analogues of indazolium alkaloids to obtaining hydride in acetonitrile

Published:2015 Issue:47 Volume:13 Page:11472-11485
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Lei Nan-Ping¹²³⁴⁵,Fu Yan-Hua¹²³⁴⁵,Zhu Xiao-Qing¹²³⁴⁵

Affiliation:

1. The State Key Laboratory of Elemento-Organic Chemistry

2. Department of Chemistry

3. Collaborative Innovation Center of Chemical Science and Engineering

4. Nankai University

5. Tianjin 300071

Abstract

A series of analogues of the natural indazolium alkaloids were designed and synthesized. The thermodynamic driving forces of the 6 elemental steps for the analogues to gain hydride in acetonitrile were determined. The reduction mechanism of indazolium alkaloids by NADH coenzyme was examined.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/OB/C5OB01715G

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