Diastereoselective aldol-type interception of phenolic oxonium ylides for the direct assembly of 2,2-disubstituted dihydrobenzofurans-Reference-Cited by-同舟云学术

Diastereoselective aldol-type interception of phenolic oxonium ylides for the direct assembly of 2,2-disubstituted dihydrobenzofurans

Published:2022 Issue:22 Volume:20 Page:4635-4639
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Hong Kemiao¹,Yang Xiangji¹,Zhang Zhijing¹,Xie Xiongda¹,Lv Xin¹,Xu Xinfang¹^ORCID,Hu Wenhao¹

Affiliation:

1. Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China

Abstract

A diastereoselective aldol-type interception of phenolic oxonium ylides with isatins provides an effective access to 2,2-disubstituted dihydrobenzofuran derivatives in high yields.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/OB/D2OB00723A

Reference47 articles.

1. Dihydrobenzofuran Neolignanamides: Laccase-Mediated Biomimetic Synthesis and Antiproliferative Activity

2. Phytochemicals Approach for Developing Cancer Immunotherapeutics

3. Bioactive benzofuran derivatives: An insight on lead developments, radioligands and advances of the last decade

4. Comparative Antiproliferative and Apoptotic Effects of Resveratrol, ϵ-viniferin and Vine-shots Derived Polyphenols (Vineatrols) on Chronic B Lymphocytic Leukemia Cells and Normal Human Lymphocytes

5. Isolation of two highly potent and non-toxic inhibitors of human immunodeficiency virus type 1 (HIV-1) integrase from Salvia miltiorrhiza

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