Hypotoxic amphiphilic polymers with high fluoride content as oxygen carriers enhance photodynamic therapy against hypoxic tumors

Author:

Zhang Jun-an1ORCID,Sheng Jiang-feng2,Haddleton David3ORCID,Wilson Paul3ORCID,Mo Yong-jie1,Li Hong-li1,Zhao Hong-lei4,Zhu Lin-hua13,Dai Chun-yan13ORCID,Zhao Lin-lu5ORCID

Affiliation:

1. Key Laboratory of Tropical Medicinal Resource Chemistry of Ministry of Education, Key Laboratory of Tropical Medicinal Plant Chemistry of Hainan Province, Key Laboratory of Functional Organic Polymers of Haikou, Tropical Functional Polymer Materials Engineering Research Center of Hainan, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou, Hainan, 571158, China

2. Jiangsu Jitri Carbon Fiber and Composite Application Technologies Research Institute Co., Ltd, 213000, Changzhou, China

3. Department of Chemistry, University of Warwick Coventry, CV4 7AL, UK

4. Hainan Liansu Industrial Technology Co., Ltd, Dingan, Hannan, 571200, China

5. Key Laboratory of Emergency and Trauma of Ministry of Education, The Fist Affiliated Hospital, Hainan Medical University, Haikou, 571199, China

Abstract

Synthesis of the amphiphilic fluorinated polymer PEGA-PFOEA (PEGAF) and its application in enhancing photodynamic therapy.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

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