Enhanced biosensing of tumor necrosis factor-alpha based on aptamer-functionalized surface plasmon resonance substrate and Goos

Enhanced biosensing of tumor necrosis factor-alpha based on aptamer-functionalized surface plasmon resonance substrate and Goos–Hänchen shift

Published:2024 Issue:10 Volume:149 Page:3017-3025
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Borg Kathrine Nygaard¹²^ORCID,Jaffiol Rodolphe²,Ho Yi-Ping¹³⁴⁵^ORCID,Zeng Shuwen²^ORCID

Affiliation:

1. Department of Biomedical Engineering, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China

2. Light, Nanomaterials & Nanotechnologies (L2n), CNRS-UMR 7076, University of Technology of Troyes, 10000, Troyes, France

3. Centre for Biomaterials, The Chinese University of Hong Kong, Hong Kong SAR, China

4. Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics, Hong Kong SAR, China

5. State Key Laboratory of Marine Pollution, City University of Hong Kong, Hong Kong SAR, China

Abstract

This study introduces an aptamer-based surface plasmon resonance biosensor for biomolecule detection, showcasing heightened sensitivity with the Goos–Hänchen shift occurring upon analyte-aptamer binding.

Funder

Agence Nationale de la Recherche

Campus France

Chinese University of Hong Kong

City University of Hong Kong

Université de Technologie de Troyes

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/AN/D4AN00194J

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