Cu-Catalyzed ligand-free synthesis of rosuvastatin based novel indole derivatives as potential anticancer agents

Author:

Kumar K. Shiva1234,Rajesham Bandari1234,Ramulu Meesa Siddi1234,Bhaskar Boyapally1234,Dash Surjya Narayan5678,Ashfaq Mohd Ashraf910114,Nagarapu Raju910114,Khan Aleem Ahmed910114,Lehtonen Sanna5678ORCID,Pal Manojit1213144

Affiliation:

1. Department of Chemistry

2. Osmania University

3. Hyderabad-500 007

4. India

5. Department of Pathology

6. University of Helsinki

7. Helsinki

8. Finland

9. Central Laboratory for Stem Cell Research and Translational Medicine

10. CLRD Deccan Colleges of Medical Sciences

11. Hyderabad-500 058

12. Dr Reddy's Institute of Life Sciences

13. Hyderabad Central University

14. Hyderabad-500 046

Abstract

Rosuvastatin based indoles showed anti-proliferative and apoptotic activities and an increase of p21 mRNA expression levels in zebrafish larvae.

Funder

Council of Scientific and Industrial Research

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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