Silver-catalyzed decarboxylative radical allylation of α,α-difluoroarylacetic acids for the construction of CF2

Silver-catalyzed decarboxylative radical allylation of α,α-difluoroarylacetic acids for the construction of CF2–allyl bonds

Published:2021 Issue:9 Volume:19 Page:2023-2029
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Wang Pingyang¹²³⁴,Du Pengcheng¹²³⁴,Sun Qianqian¹²³⁴,Zhang Jianhua⁵⁶²³⁴,Deng Hongmei⁷²³⁴,Jiang Haizhen¹²³⁴⁸^ORCID

Affiliation:

1. Department of Chemistry

2. Shanghai University

3. Shanghai

4. PR China

5. Key Laboratory of Advanced Display and System Application

6. Ministry of Education

7. Laboratory for Microstructures

8. Key Laboratory of Organofluorine Chemistry

Abstract

An efficient silver-catalyzed method of decarboxylative radical allylation of α,α-difluoroarylacetic acids has been developed to construct CF₂–allyl bonds in aqueous CH₃CN solution under the mild reaction conditions.

Funder

Ministry of Science and Technology of the People's Republic of China

Science and Technology Commission of Shanghai Municipality

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/OB/D0OB02546A

Reference48 articles.

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2. Some aspects of radical chemistry in the assembly of complex molecular architectures

3. Photocatalytic decarboxylative alkylations mediated by triphenylphosphine and sodium iodide

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