A pH-responsive dissociable mesoporous silica-based nanoplatform enabling efficient dual-drug co-delivery and rapid clearance for cancer therapy-Reference-Cited by-同舟云学术

A pH-responsive dissociable mesoporous silica-based nanoplatform enabling efficient dual-drug co-delivery and rapid clearance for cancer therapy

Published:2020 Issue:12 Volume:8 Page:3418-3429
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

He Yongju¹²³⁴^ORCID,Shao Linjie¹²³⁴,Usman Ibrahim¹²³⁴,Hu Yao¹²³⁴,Pan Anqiang¹²³⁴^ORCID,Liang Shuquan¹²³⁴,Xu Hui⁵⁶⁷⁸⁴^ORCID

Affiliation:

1. School of Material Science and Engineering

2. Central South University

3. Changsha

4. China

5. State Key Laboratory of Natural Medicines

6. Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases

7. China Pharmaceutical University

8. Nanjing 210009

Abstract

A pH-responsive dissociable mesoporous silica-based cluster with efficient dual-drug co-delivery for combinational cancer therapy, tumor accumulation via its large size-favored EPR effect and rapid clearance by its acid-triggered dissociation.

Funder

Central Universities in China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2020/BM/D0BM00204F

Reference37 articles.

1. Role of Nanoparticle Mechanical Properties in Cancer Drug Delivery

2. Polymer nanoparticles for the intravenous delivery of anticancer drugs: the checkpoints on the road from the synthesis to clinical translation

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4. Nanomachines and Other Caps on Mesoporous Silica Nanoparticles for Drug Delivery

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