PoCOsteo: generic novel platform for bone turnover marker measurement & monitoring

Author:

Khashayar Patricia12ORCID,Lopes Paula13,Ragaert Peter4,Hoogenboom Richard5ORCID,Latta Daniel6,Gransee Rainer6,Lenartowicz Daniel7,Biggs Phil7,Etxebarria Ikerne8,Luegger Barbara9,Obermayer-Pietsch Barbara9,Dimai Hans Peter9,Vanfleteren Jan1ORCID

Affiliation:

1. Center for Microsystems Technology, Imec & Ghent University, Zwijnaarde, Gent, Belgium

2. International Institute for Biosensing, University of Minnesota, Minneapolis, USA

3. International Iberian Nanotechnology Laboratory, Braga, Portugal

4. Research Unit Food Microbiology and Food Preservation, Faculty of Bioscience Engineering, Ghent University, Gent, Belgium

5. Supramolecular Chemistry Group, Centre of Macromolecular Chemistry, Department of Organic and Macromolecular Chemistry, Ghent University, Ghent 9000, Belgium

6. Fraunhofer-Institut für Mikrotechnik und Mikrosysteme IMM, Mainz, Germany

7. Labman Co., Middlesbrough, TS9 5NQ, UK

8. TE Connectivity, 20500 Arrasate, Gipuzkoa, Spain

9. Department of Internal Medicine, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Styria, Austria

Abstract

OsteoLab immunosensors can simultaneously measure two bone turnover markers in a single finger prick sample with high sensitivity, in real time and beyond the clinical reference range. They can be stored at room temperature for more than six months.

Funder

H2020 European Institute of Innovation and Technology

Publisher

Royal Society of Chemistry (RSC)

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