Highly selective cross-coupling reactions of 1,1-dibromoethylenes with alkynylaluminums for the synthesis of aryl substituted conjugated enediynes and unsymmetrical 1,3-diynes-Reference-Cited by-同舟云学术

Highly selective cross-coupling reactions of 1,1-dibromoethylenes with alkynylaluminums for the synthesis of aryl substituted conjugated enediynes and unsymmetrical 1,3-diynes

Published:2022 Issue:21 Volume:12 Page:13314-13318
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Wu Kun¹,Wu Chuan¹,Jia Xiao-Ying¹,Zhou Lin¹^ORCID,Li Qing-Han¹

Affiliation:

1. Key Laboratory of General Chemistry of the National Ethnic Affairs Commission, College of Chemistry and Environment, Southwest Minzu University, Chengdu 610041, P. R. China

Abstract

A highly efficient method for the synthesis of aryl substituted conjugated enediynes and unsymmetrical 1,3-diynes via selective cross-coupling reactions of 1,1-dibromoethylenes with alkynylaluminums has been successfully developed.

Funder

National Natural Science Foundation of China

Southwest Minzu University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/RA/D2RA02127G

Reference70 articles.

1. Designed Enediynes: A New Class of DNA-Cleaving Molecules with Potent and Selective Anticancer Activity

2. Copper-Catalyzed Coupling of Alkynes with Alkenyl Halides