The one-step synthesis and surface functionalization of dumbbell-like gold–iron oxide nanoparticles: a chitosan-based nanotheranostic system

Author:

Kostevsek Nina1234,Locatelli Erica56789,Garrovo Chiara10119,Arena Francesca121314159,Monaco Ilaria56789,Nikolov Ivaylo Petrov16179,Sturm Saso1234,Zuzek Rozman Kristina1234,Lorusso Vito18159,Giustetto Pierangela18159,Bardini Paola121314159,Biffi Stefania10119,Comes Franchini Mauro56789ORCID

Affiliation:

1. Department for Nanostructured Materials K-7

2. Jozef Stefan Institute

3. Jamova cesta 39 SI-1000

4. Slovenia

5. Department of Industrial Chemistry “Toso Montanari”

6. University of Bologna

7. Viale Risorgimento 4

8. 40136 Bologna

9. Italy

10. Institute for Maternal and Child Health-IRCCS “Burlo Garofolo”

11. 34137 Trieste

12. Department of Molecular Biotechnology and Health Sciences

13. Center of Excellence for Preclinical Imaging (CEIP)

14. University of Torino

15. Colleretto Giacosa

16. Elettra-Sincrotrone Trieste

17. Trieste

18. Ephoran – Multi-Imaging Solutions – Bioindustry Park Silvano Fumero

Abstract

The first one-step synthesis of dumbbell-like gold–iron oxide nanoparticles has been reported here. Surface functionalization with a biocompatible chitosan matrix allowed us to obtain a novel targetable diagnostic and therapeutic tool.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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