Therapeutic effects of a walnut-derived peptide on NLRP3 inflammasome activation, synaptic plasticity, and cognitive dysfunction in T2DM mice

Author:

Li Yanru1,Dang Qiao1,Shen Yue1,Guo Linxin1,Liu Chunlei1,Wu Dan1,Fang Li1,Leng Yue1ORCID,Min Weihong23

Affiliation:

1. College of Food Science and Engineering, Jilin Agricultural University, Changchun 130118, P. R. China

2. College of Food and Health, Zhejiang A & F University, Hangzhou 311300, P.R. China

3. National Grain Industry (High-Quality Rice Storage in Temperate and Humid Region) Technology Innovation Center, Hangzhou 311300, China

Abstract

NLRP3 inflammasome activation plays a key role in the development of diabetes-induced cognitive impairment.

Funder

Jilin Provincial Scientific and Technological Development Program

Publisher

Royal Society of Chemistry (RSC)

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