High-depth fluorescence imaging using a two-photon FRET system for mitochondrial pH in live cells and tissues

Author:

Chang Min Jung123,Kim Kyutae453,Park Kyun Seob453,Kang Ji Su673,Lim Chang Su673,Kim Hwan Myung673ORCID,Kang Chulhun453,Lee Min Hee123ORCID

Affiliation:

1. Department of Chemistry, Sookmyung Women's University

2. Seoul

3. Korea

4. The School of East-West Medical Science, Kyung Hee University

5. Yongin

6. Department of Chemistry, Ajou University

7. Suwon

Abstract

We developed a fluorescent pH probe (1) capable of two-photon excitation and far-visible-emission based on FRET, composed of naphthalimide–piperazine–rhodamine.

Funder

National Research Foundation of Korea

Sookmyung Women's University

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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