Are proteins a redundant ontology? Epistemological limitations in the analysis of multistate species-Reference-Cited by-同舟云学术

Are proteins a redundant ontology? Epistemological limitations in the analysis of multistate species

Published:2014 Issue:6 Volume:10 Page:1228-1235
ISSN:1742-206X
Container-title:Mol. BioSyst.
language:en
Short-container-title:Mol. BioSyst.

Author:

Corfe Bernard M.¹²³⁴⁵,Evans Caroline A.⁶⁴⁵⁷⁸

Affiliation:

1. Molecular Gastroenterology Research Group

2. Academic Unit of Surgical Oncology

3. Department of Oncology

4. University of Sheffield

5. UK

6. Chemical Engineering at the Life Science Interface (ChELSI) Institute

7. Biological and Systems Engineering Group

8. ChELSI Institute

Abstract

Do proteins really exist? Post-translational modification data depositions represent an insurmountable epistemological challenge. A framework to describe “proteins” as metabolic pathways or networks, in a conceptual continuum with metabolites, is proposed.

Publisher

Royal Society of Chemistry (RSC)

Subject

Molecular Biology,Biotechnology

Link

http://pubs.rsc.org/en/content/articlepdf/2014/MB/C3MB70558G

Reference48 articles.

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4. Analysis of posttranslational modifications of proteins by tandem mass spectrometry

5. Introduction to Glycosylation and Mass Spectrometry

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