Gut microbiota–bile acid axis mediated the beneficial associations between dietary lignans and hyperuricemia: a prospective study

Author:

Zhuo Lai-Bao1,Yang Yingdi1,Xiao Congmei23,Li Fanqin1,Lin Lishan1,Xi Yue1,Fu Yuanqing23,Zheng Ju-Sheng2ORCID,Chen Yu-ming1ORCID

Affiliation:

1. Department of Epidemiology, Guangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China

2. Zhejiang Key Laboratory of Multi-Omics in Infection and Immunity, School of Medicine and School of Life Sciences, Westlake University, Hangzhou 310030, China

3. Shenzhen Bao'an Center for Chronic Diseases Control, Shenzhen, China

Abstract

Dietary lignan consumption was inversely associated with the incidence of hyperuricemia, with the gut microbiota–bile acid axis potentially mediating this relationship.

Funder

National Natural Science Foundation of China

Sun Yat-sen University

Publisher

Royal Society of Chemistry (RSC)

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