Where is it and how much? Mapping and quantifying elements in single cells

Author:

Malucelli Emil1234,Fratini Michela56478,Notargiacomo Andrea910114,Gianoncelli Alessandra12134,Merolle Lucia12134,Sargenti Azzurra1234,Cappadone Concettina1234,Farruggia Giovanna123414,Lagomarsino Stefano141541617,Iotti Stefano123414

Affiliation:

1. Department of Pharmacy and Biotechnology

2. University of Bologna

3. Bologna 40127

4. Italy

5. Institute of Nanotechnology-CNR c/o Physics Department at ‘Sapienza’ University

6. 00185 Rome

7. IRCCS Fondazione Santa Lucia

8. 00179 Roma

9. Institute for Photonics and Nanotechnology

10. Consiglio Nazionale delle Ricerche

11. 00156 Rome

12. Elettra - Sincrotrone Trieste

13. 34149 Basovizza

14. National Institute of Biostructures and Biosystems

15. 00136 Rome

16. Institute of Chemical-Physical Processes

17. Sapienza University of Rome

Abstract

The biological function of a chemical element in cells not only requires the determination of its intracellular quantity, but also the spatial distribution of its concentration.

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Reference103 articles.

1. Imaging trace element distributions in single organelles and subcellular features

2. Lehninger principles of biochemistry: [includes CD-ROM: Understand! Biochemistry], ed. D. L. Nelson, M. M. Cox and A. L. Lehninger, Worth Publ, New York, NY, 3rd edn, 2003, printing

3. Modern nutrition in health and disease, ed. M. E. Shils, Williams & Wilkins, Baltimore, 9th edn, 1999, p. 1951

4. A. S. Prasad , Essential and Toxic Element: Trace Elements in Human Health and Disease. Elsevier, 2013, 544p

5. Quantitative micro-analysis of metal ions in subcellular compartments of cultured dopaminergic cells by combination of three ion beam techniques

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