A multiscale screening strategy for the identification of novel xanthine oxidase inhibitors based on the pharmacological features of febuxostat analogues-Reference-Cited by-同舟云学术

A multiscale screening strategy for the identification of novel xanthine oxidase inhibitors based on the pharmacological features of febuxostat analogues

Published:2022 Issue:14 Volume:46 Page:6549-6559
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Zhai Na¹,Chen Yanming¹,Wang Chenchen¹,Wu Fengshou¹^ORCID,Luo Xiaogang¹²^ORCID,Ju Xiulian¹,Liu Hui³,Liu Genyan¹^ORCID

Affiliation:

1. Key Laboratory for Green Chemical Process of Ministry of Education, Hubei Key Laboratory of Novel Reactor and Green Chemical Technology, School of Chemical Engineering and Pharmacy, Wuhan Institute of Technology, Wuhan 430205, P. R. China

2. School of Materials Science and Engineering, Zhengzhou University, No. 100 Science Avenue, Zhengzhou City, 450001, Henan Province, P. R. China

3. Department of Hematology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, P. R. China

Abstract

Two compounds as potential XOI hits were identified by a novel screening strategy based on the pharmacophores of well-known scaffolds.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2022/NJ/D2NJ00115B