Kinetics of cisplatin binding to short r(GG) containing miRNA mimics – influence of Na+versus K+, temperature and hydrophobicity on reactivity
Author:
Affiliation:
1. Biochemistry and Structural Biology
2. KILU
3. Lund University
4. SE-221 00 Lund
5. Sweden
Abstract
Nucleic acids are well recognized targets for platinum-based anticancer drugs, with RNA and DNA being kinetically comparable.
Publisher
Royal Society of Chemistry (RSC)
Subject
Inorganic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/DT/C5DT00663E
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