Anti-amyloidogenic amphipathic arginine-dehydrophenylalanine spheres capped selenium nanoparticles as potent therapeutic moieties for Alzheimer's disease-Reference-Cited by-同舟云学术

Anti-amyloidogenic amphipathic arginine-dehydrophenylalanine spheres capped selenium nanoparticles as potent therapeutic moieties for Alzheimer's disease

Published:2023 Issue:30 Volume:15 Page:12748-12770
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Kour Avneet¹²,Tiwari Virendra³,Aggarwal Nidhi¹,Sekhar Panda Himanshu¹,Kumar Ashwani²,Tiwari Siddharth⁴,Chauhan Virander Singh⁵^ORCID,Shukla Shubha³,Panda Jiban Jyoti¹^ORCID

Affiliation:

1. Institute of Nano Science and Technology, Mohali, Punjab 140306, India

2. University Institute of Pharmaceutical Sciences, Punjab University, Chandigarh 160014, India

3. CSIR-Central Drug Research Institute, Sector 10, Jankipuram Extension, Sitapur Road, Lucknow 226031, India

4. National Agri-Food Biotechnology Institute (NABI), Mohali, Punjab 140308, India

5. International Centre for Genetic Engineering and Biotechnology, New Delhi 110067, India

Abstract

Synthesis of RΔF nanosphere-capped SeNPs with anti-amyloidogenic potency towards peptide aggregates. NPs can cross the BBB, exhibit protective effects against STZ-induced cytotoxicity in neuronal cells, and improve cognitive performance in STZ-induced rat AD models.

Funder

Council of Scientific and Industrial Research, India

Department of Biotechnology, Ministry of Science and Technology, India

Indian Council of Medical Research

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2023/NR/D3NR01558K

Reference88 articles.