Nano-Affi: a solution-phase, label-free, colorimetric aptamer affinity assay based on binding-inhibited aggregation of gold nanoparticles
Author:
Affiliation:
1. Department of Chemistry
2. Capital Normal University
3. Beijing
4. China
5. State Key Laboratory of Toxicology and Medical Countermeasures
6. Beijing Institute of Pharmacology and Toxicology
Abstract
The ideal way to assess aptamer affinity is when both aptamer and target are in a native state, without the unpredictable interference associated with labelling and surface immobilization.
Funder
National Natural Science Foundation of China
Natural Science Foundation of Beijing Municipality
Publisher
Royal Society of Chemistry (RSC)
Subject
Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/AN/D0AN00827C
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1. Systematic Evolution of Ligands by Exponential Enrichment: RNA Ligands to Bacteriophage T4 DNA Polymerase
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5. Aptamer-based assays and aptasensors for detection of pathogenic bacteria in food samples
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