Synthesis and in vitro antimicrobial activity evaluation of coumarin-3-carboxylic acids obtained via cascade reaction using chitosan as a recyclable catalyst

Abstract

As a recyclable catalyst, Chitosan promotes the rapid synthesis of coumarin-3-carboxylic acids via Knoevenagel-intramolecular cascade reaction in good yields. The compounds showed potent antifungal and antimicrobial activities in vitro evaluations.