Synthesis of ciprofloxacin-linked 1,2,3-triazole conjugates as potent antibacterial agents using click chemistry: exploring their function as DNA gyrase inhibitors <i>via in silico</i>- and <i>in vitro</i>-based studies-Reference-Cited by-同舟云学术

Synthesis of ciprofloxacin-linked 1,2,3-triazole conjugates as potent antibacterial agents using click chemistry: exploring their function as DNA gyrase inhibitors via in silico- and in vitro-based studies

Published:2024 Issue:24 Volume:14 Page:17051-17070
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Patel Upendra Kumar¹^ORCID,Tiwari Punit²,Tilak Ragini²,Joshi Gaurav³,Kumar Roshan⁴,Agarwal Alka¹^ORCID

Affiliation:

1. Department of Medicinal Chemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasi, UP-221005, India

2. Department of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, UP-221005, India

3. Department of Pharmaceutical Sciences, Hemvati Nandan Bahuguna Garhwal University (Central University), Dist. Garhwal (Uttarakhand), Srinagar-246174, India

4. Department of Microbiology, Central University of Punjab, Ghudda, Bathinda-151401, India

Abstract

The antibacterial efficacy of some newly developed C-3 carboxylic group-containing ciprofloxacin-linked 1,2,3-triazole conjugates was studied.

Funder

Human Resource Development Group, Council of Scientific And Industrial Research

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/RA/D4RA01332H

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5. G. L.Patrick , An Introduction to Medicinal Chemistry , Oxford University Press , Oxford , 3rd edn, 2005