Addressing the gaps in homeostatic mechanisms of copper and copper dithiocarbamate complexes in cancer therapy: a shift from classical platinum-drug mechanisms-Reference-Cited by-同舟云学术

Addressing the gaps in homeostatic mechanisms of copper and copper dithiocarbamate complexes in cancer therapy: a shift from classical platinum-drug mechanisms

Published:2023 Issue:18 Volume:52 Page:5823-5847
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Njenga Lydia W.¹,Mbugua Simon N.²^ORCID,Odhiambo Ruth A.¹^ORCID,Onani Martin O.³^ORCID

Affiliation:

1. Department of Chemistry, University of Nairobi, P.O. Box 30197-00100, Nairobi, Kenya

2. Department of Chemistry, Kisii University, P.O. Box 408-40200, Kisii, Kenya

3. Department of Chemical Sciences, University of the Western Cape, Private Bag X17, Belville, 7535, South Africa

Abstract

This review will focus on copper homeostasis in mammalian cells and on our current understanding of copper dysregulation in cancer and recent therapeutic breakthroughs using copper coordination complexes as anticancer drugs.

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/DT/D3DT00366C

Reference301 articles.

1. Targeting copper induced oxidative damage to proteins by ligation: a novel approach towards chelation therapy for oxidative stress disorders

2. Current Biomedical Use of Copper Chelation Therapy

3. Abnormal Copper Homeostasis: Mechanisms and Roles in Neurodegeneration

4. Copper dyshomoeostasis in Parkinson's disease: implications for pathogenesis and indications for novel therapeutics

Cited by 7 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Facile synthesis of intelligent semi-salamo Cu (II) complex with glutathione depletion for enhanced chemodynamic therapy;Journal of Molecular Structure;2024-10

2. Recent advances in copper homeostasis-involved tumor theranostics;Asian Journal of Pharmaceutical Sciences;2024-09

3. Synthesis, structure and in vitro anticancer activity of copper(II) and platinum(II) complexes with pyrrol-appended dipicolylamine ligand;Inorganic Chemistry Communications;2024-08

4. 8-hydroxyquinoline-N-oxide copper(II)- and zinc(II)-phenanthroline and bipyridine coordination compounds: Design, synthesis, structures, and antitumor evaluation;Journal of Inorganic Biochemistry;2024-02

5. Correction: Addressing the gaps in homeostatic mechanisms of copper and copper dithiocarbamate complexes in cancer therapy: a shift from classical platinum-drug mechanisms;Dalton Transactions;2024