Transition metal complexes as self-activating chemical nucleases: proficient DNA cleavage without any exogenous redox agents

Author:

Kumar Pramod1ORCID,Tomar Sunil2,Kumar Krishan3,Kumar Sushil4ORCID

Affiliation:

1. Department of Chemistry, Mahamana Malviya College Khekra (Baghpat), C.C.S. University Meerut, India

2. Department of Zoology, Mahamana Malviya College Khekra (Baghpat), C.C.S. University Meerut, India

3. Department of Chemistry, Motilal Nehru College, South Campus University of Delhi, New Delhi, India

4. Department of Chemistry, School of Engineering, University of Petroleum and Energy Studies (UPES), Dehradun-248007, Uttarakhand, India

Abstract

This perspective presents DNA cleavage via self-activation based on transition metal complexes employing copper, zinc and iron with their mechanistic investigation.

Funder

Department of Science and Technology, Ministry of Science and Technology, India

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

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