Energy framework and solubility: a new predictive model in the evaluation of the structure–property relationship of pharmaceutical solid forms-Reference-Cited by-同舟云学术

Energy framework and solubility: a new predictive model in the evaluation of the structure–property relationship of pharmaceutical solid forms

Published:2022 Issue:44 Volume:24 Page:7803-7812
ISSN:1466-8033
Container-title:CrystEngComm
language:en
Short-container-title:CrystEngComm

Author:

Freitas Jennifer T. J.¹^ORCID,Diniz Luan F.¹²,Gomes Daniele S.¹,de Paula Pedro M. A. F.¹,de Castro Sérgio H. A.¹,Martins Larissa S.¹,Silva Daniely F.¹,Horta Ana L. M.¹^ORCID,Guimarães Felipe A. S.¹,Calisto Victória F. M.¹^ORCID,Diniz Renata¹^ORCID

Affiliation:

1. Grupo de Cristalografia Química (GCQ), Departamento de Química, Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, 31270-901-Belo Horizonte, MG, Brazil

2. Laboratório de Controle de Qualidade de Medicamentos e Cosméticos, Departamento de Produtos Farmacêuticos, Faculdade de Farmácia, Universidade Federal de Minas Gerais, 31270-901, Belo Horizonte, MG, Brazil

Abstract

Crystal structures with lower interaction energy tend to present higher aqueous solubility.

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Fundação de Amparo à Pesquisa do Estado de Minas Gerais

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Materials Science,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/CE/D2CE00818A

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