Facile synthetic approach towards vasorelaxant active 4-hydroxyquinazoline-4-carboxamides-Reference-Cited by-同舟云学术

Facile synthetic approach towards vasorelaxant active 4-hydroxyquinazoline-4-carboxamides

Published:2019 Issue:49 Volume:9 Page:28534-28540
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Aziz Marian N.¹²³⁴,Panda Siva S.⁵⁶⁷⁸^ORCID,Shalaby ElSayed M.⁹¹⁰²³⁴^ORCID,Fawzy Nehmedo G.¹²³⁴,Girgis Adel S.¹²³⁴^ORCID

Affiliation:

1. Department of Pesticide Chemistry

2. National Research Centre

3. Giza 12622

4. Egypt

5. Department of Chemistry & Physics

6. Augusta University

7. Augusta

8. USA

9. X-Ray Crystallography Lab

10. Physics Division

Abstract

A set of vasorelaxant active 4-hydroxyquinazoline-4-carboxamides was obtained in a novel synthetic approach via secondary amine nucleophilic reaction with 2,3-dioxoindoline-1-carboxamides.

Funder

National Research Centre

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/RA/C9RA04321G

Reference39 articles.

1. Recent advancements of 4-aminoquinazoline derivatives as kinase inhibitors and their applications in medicinal chemistry

2. An overview of quinazolines: Pharmacological significance and recent developments

3. Quinazolines and quinazolinones as ubiquitous structural fragments in medicinal chemistry: An update on the development of synthetic methods and pharmacological diversification

4. Synthetic approaches, functionalization and therapeutic potential of quinazoline and quinazolinone skeletons: The advances continue

5. Quinazoline derivatives as anticancer drugs: a patent review (2011 – present)

Cited by 9 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Overview of Piperidine and Morpholine Derivatives as Promising Sources of Biologically Active Compounds (Review);Drug development & registration;2023-05-27

2. Novel Curcumin Mimics: Design, Synthesis, Biological Properties and Computational Studies of Piperidone‐Piperazine Conjugates;ChemistrySelect;2022-08-18

3. Synthesis, Antibacterial Evaluation, and Computational Studies of a Diverse Set of Linezolid Conjugates;Pharmaceuticals;2022-02-03

4. Design and synthesis of ibuprofen-quinoline conjugates as potential anti-inflammatory and analgesic drug candidates;Bioorganic Chemistry;2022-02

5. New hydronaphthalene-sulfonamide derivatives: Synthesis, antimicrobial evaluation and QSAR study;Journal of Molecular Structure;2021-12