Collision induced unfolding and molecular dynamics simulations of norovirus capsid dimers reveal strain-specific stability profiles-Reference-Cited by-同舟云学术

Collision induced unfolding and molecular dynamics simulations of norovirus capsid dimers reveal strain-specific stability profiles

Published:2024 Issue:17 Volume:26 Page:13094-13105
ISSN:1463-9076
Container-title:Physical Chemistry Chemical Physics
language:en
Short-container-title:Phys. Chem. Chem. Phys.

Author:

Brodmerkel Maxim N.¹^ORCID,Thiede Lars²³,De Santis Emiliano¹⁴^ORCID,Uetrecht Charlotte²³^ORCID,Caleman Carl⁴⁵^ORCID,Marklund Erik G.¹^ORCID

Affiliation:

1. Department of Chemistry - BMC, Uppsala University, 75123 Uppsala, Sweden

2. CSSB Centre for Structural Systems Biology, Deutsches Elektronen-Synchrotron DESY, Leibniz Institute of Virology (LIV), Notkestrasse 85, 22607 Hamburg, Germany

3. Institute of Chemistry and Metabolomics, University of Lübeck, Ratzeburger Allee 160, 23562 Lübeck, Germany

4. Department of Physics and Astronomy, Uppsala University, 75120 Uppsala, Sweden

5. Center for Free-Electron Laser Science CFEL, Deutsches Elektronen-Synchrotron, DESY, Notkestrasse 85, 22607 Hamburg, Germany

Abstract

Ion mobility mass spectrometry and molecular dynamics simulations reveal strain-dependent stability and unfolding in the VP1 dimer from the norovirus capsid.

Funder

Vetenskapsrådet

Bundesministerium für Bildung und Forschung

Horizon 2020 Framework Programme

European Commission

Uppsala Multidisciplinary Center for Advanced Computational Science

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/CP/D3CP06344E

Reference74 articles.

1. Structural Symmetry and Protein Function

2. A hydrophobic ratchet entrenches molecular complexes

3. N. F.Steinmetz , T.Lin , G.Lomonossoff and J.Johnson , Structure-based engineering of an icosahedral virus for nanomedicine and nanotechnology , Springer , 2009

4. Acute gastroenteritis in children

5. Norovirus Gastroenteritis

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. High-Performance Molecular Dynamics Simulations for Native Mass Spectrometry of Large Protein Complexes with the Fast Multipole Method;Analytical Chemistry;2024-09-04