Bone formation promoted by bone morphogenetic protein-2 plasmid-loaded porous silica nanoparticles with the involvement of autophagy-Reference-Cited by-同舟云学术

Bone formation promoted by bone morphogenetic protein-2 plasmid-loaded porous silica nanoparticles with the involvement of autophagy

Published:2019 Issue:45 Volume:11 Page:21953-21963
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Xu Xiaowei¹²³⁴^ORCID,Sun Maolei¹²³⁴,Wang Dandan¹²³⁴,Bu Wenhuan¹²³⁴,Wang Zilin¹²³⁴,Shen Yuqin¹²³⁴,Zhang Kai⁵⁶²⁷⁴^ORCID,Zhou Ding⁸⁹¹⁰¹¹¹²^ORCID,Yang Bai⁵⁶²⁷⁴^ORCID,Sun Hongchen¹¹³¹⁴⁴^ORCID

Affiliation:

1. School and Hospital of Stomatology

2. Jilin University

3. Changchun 130021

4. P. R. China

5. AState Key Laboratory of Supramolecular Structure and Materials

6. College of Chemistry

7. Changchun 130012

8. State Key Laboratory of Luminescence and Applications

9. Changchun Institute of Optics

10. Fine Mechanics and Physics

11. Chinese Academy of Sciences

12. Changchun 130033

13. China Medical University

14. Shenyang 110122

Abstract

Bone morphogenetic protein-2 plasmid was encapsulated by polyethylenimine-modified porous silica nanoparticles, which promoted osteogenic differentiation and increased calcium deposition with the involvement of autophagy.

Funder

National Basic Research Program of China

National Natural Science Foundation of China

China Association for Science and Technology

China Postdoctoral Science Foundation

Program for Jilin University Science and Technology Innovative Research Team

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2019/NR/C9NR07017F