Metal-free regioselective mono- and poly-halogenation of 2-substituted indazoles-Reference-Cited by-同舟云学术

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Metal-free regioselective mono- and poly-halogenation of 2-substituted indazoles

Published:2023 Issue:8 Volume:13 Page:4958-4962
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Zhang Changjun¹,Wei Tingting¹,Yu Zhichen¹,Ding Yuxin¹,Su Weike²,Xie Yuanyuan¹²³^ORCID

Affiliation:

1. College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, P. R. China

2. Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaeuticals, Zhejiang University of Technology, Hangzhou 310014, P. R. China

3. Key Laboratory of Pharmaceutical Engineering of Zhejiang Province, Hangzhou 310014, China

Abstract

An unprecedented metal-free regioselective halogenation of 2H-indazoles is reported, and not only realizes the highly selective synthesis of mono-halogenated products, but also complete poly-halogenations.

Funder

National Natural Science Foundation of China

National Key Research and Development Program of China

China Postdoctoral Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/RA/D2RA07398F

Reference39 articles.

1. BIOSYNTHESIS OF HALOGENATED METABOLITES BY BACTERIA

2. Current Methods for Asymmetric Halogenation of Olefins

3. Microbial degradation of halogenated aromatics: molecular mechanisms and enzymatic reactions

4. Regioselectively Halogenated Expanded Porphyrinoids as Building Blocks for Constructing Porphyrin–Porphyrinoid Heterodyads with Tunable Energy Transfer

5. Trihaloisocyanuric acids in ethanol: an eco-friendly system for the regioselective halogenation of imidazo-heteroarenes

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1. Regioselective C3-halogenations of N-(pyrazolo[1,5-a]pyrimidin-7-yl)acetamides;Tetrahedron;2024-01

2. Electrochemical C3 acyloxylation reactions of 2H-indazoles with carboxylic acids via C(sp²)–O coupling;Green Chemistry;2023

3. Regioselective C3-Halogenation of Pyrazolo[1,5- a ]Pyrimidines;2023

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