Direct phosphorylation of benzylic C–H bonds under transition metal-free conditions forming sp<sup>3</sup>C

Direct phosphorylation of benzylic C–H bonds under transition metal-free conditions forming sp³C–P bonds

Published:2022 Issue:29 Volume:12 Page:18441-18444
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Li Qiang¹^ORCID,Zhao Chang-Qiu¹,Chen Tieqiao²^ORCID,Han Li-Biao²³^ORCID

Affiliation:

1. College of Chemistry and Chemical Engineering, Liaocheng University, No. 1, Hunan Road, Liaocheng, Shandong 252059, China

2. Key Laboratory of Ministry of Education for Advanced Materials in Tropical Island Resources, Hainan Provincial Key Lab of Fine Chem, Hainan Provincial Fine Chemical Engineering Research Center, Hainan University, Haikou 570228, China

3. Zhejiang Yanfan New Materials Co., Ltd., Shangyu, Zhejiang Province 312369, China

Abstract

Direct phosphorylation of benzylic C–H bonds with secondary phosphine oxides was first realized. The reaction was performed in organo/aqueous biphasic system and under transition metal-free conditions, proceeding via the cross dehydrogenative coupling.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/RA/D2RA02812C

Reference103 articles.

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4. Recent Advances in the Synthesis of Organophosphorus Compounds via Cross Coupling between Readily Available Materials and P-H Compounds

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