Biosynthesis of oxygenated brasilane terpene glycosides involves a promiscuous N-acetylglucosamine transferase

Author:

Feng Jin1234ORCID,Surup Frank5674ORCID,Hauser Maurice1234,Miller Anna1234,Wennrich Jan-Peer5674ORCID,Stadler Marc5674ORCID,Cox Russell J.1234ORCID,Kuhnert Eric1234ORCID

Affiliation:

1. Institute for Organic Chemistry and Centre for Biomolecular Drug Research (BMWZ)

2. Leibniz University Hannover

3. Hannover 30167

4. Germany

5. Department Microbial Drugs

6. Helmholtz Centre for Infection Research (HZI)

7. 38124 Braunschweig

Abstract

The biosynthesis of brasilane glycosides in the fungus Annulohypoxylon truncatum was investigated resulting in the characterisation of a rare type of fungal N-acetylglucosamine transferase.

Funder

China Scholarship Council

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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