Copper-catalyzed click reaction on/in live cells
Author:
Affiliation:
1. Department of Chemistry
2. University of Houston
3. Houston
4. USA
5. College of Materials Science and Engineering
6. South China University of Technology
7. Guangzhou
8. China
Abstract
A copper-catalyzed click reaction inside living mammalian cells is demonstrated with the use of a cell-penetrating peptide-tethered CuI ligand.
Funder
National Science Foundation
National Institutes of Health
University of Houston
China Scholarship Council
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/SC/C6SC02297A
Reference50 articles.
1. Click Chemistry in Complex Mixtures: Bioorthogonal Bioconjugation
2. Chemistry in living systems
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4. Cellular Incorporation of Unnatural Amino Acids and Bioorthogonal Labeling of Proteins
5. Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
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