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Simultaneous determination of tianeptine and its active metabolite tianeptine MC5 in rat plasma and brain tissue using high performance liquid chromatography/electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS)

  • Published:2018 Issue:4 Volume:10 Page:439-447
  • ISSN:1759-9660
  • Container-title:Analytical Methods
  • language:en
  • Short-container-title:Anal. Methods

Author:

El Zahar N. M.12345,Magdy N.12345,El-Kosasy A. M.12345,Beck Wayne D.678910,Callahan Patrick M.678910,Terry Alvin V.678910,Bartlett Michael G.1112131410ORCID

Affiliation:

1. Pharmaceutical Analytical Chemistry Department

2. Faculty of Pharmacy

3. Ain Shams University

4. Organization of African Unity Street

5. Abassia

6. Department of Pharmacology and Toxicology

7. Small Animal Behavior Core

8. Augusta University

9. Augusta

10. USA

11. Department of Pharmaceutical and Biomedical Sciences

12. College of Pharmacy

13. University of Georgia

14. Athens

Abstract

Validated LC-ESI-MS/MS method for tianeptine and its main metabolite in plasma and brain.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

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