Structure elucidation of the redox cofactor mycofactocin reveals oligo-glycosylation by MftF-Reference-Cited by-同舟云学术

Structure elucidation of the redox cofactor mycofactocin reveals oligo-glycosylation by MftF

Published:2020 Issue:20 Volume:11 Page:5182-5190
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Peña-Ortiz Luis¹²³⁴⁵^ORCID,Graça Ana Patrícia¹²³⁴⁵^ORCID,Guo Huijuan⁶²³⁴,Braga Daniel¹²³⁴⁵,Köllner Tobias G.⁷⁸³⁴^ORCID,Regestein Lars⁹²³⁴,Beemelmanns Christine⁶²³⁴^ORCID,Lackner Gerald¹²³⁴⁵^ORCID

Affiliation:

1. Junior Research Group Synthetic Microbiology

2. Leibniz Institute for Natural Product Research and Infection Biology (HKI)

3. 07745 Jena

4. Germany

5. Friedrich Schiller University

6. Junior Research Group Chemical Biology of Microbe-Host Interactions

7. Department of Biochemistry

8. Max Planck Institute for Chemical Ecology

9. Bio Pilot Plant

Abstract

Metabolomics-driven discovery of the novel cofactor mycofactocin in mycobacteria revealed glycosylation with a cellulose-like sugar chain, regulation in response to ethanol and redox-activity.

Funder

Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie – Hans-Knöll-Institut

Carl-Zeiss-Stiftung

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/SC/D0SC01172J

Reference29 articles.

1. Intrigues and Intricacies of the Biosynthetic Pathways for the Enzymatic Quinocofactors: PQQ, TTQ, CTQ, TPQ, and LTQ