Peptide modified gold nanoparticles for improved cellular uptake, nuclear transport, and intracellular retention-Reference-Cited by-同舟云学术

Peptide modified gold nanoparticles for improved cellular uptake, nuclear transport, and intracellular retention

Published:2014 Issue:20 Volume:6 Page:12026-12033
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Yang C.¹²³,Uertz J.⁴⁵⁶,Yohan D.¹²³,Chithrani B. D.¹²³

Affiliation:

1. Department of Physics

2. Ryerson University

3. Toronto, Canada

4. CytoVivaInc

5. Auburn

6. , USA

Abstract

A novel hyperspectral imaging technique is used to image GNPs: a combination of three peptides is used for efficient nuclear targeting and improved retention of GNPs targeted into the nucleus is shown for the first time. This is important for future cancer therapeutics as GNPs can be used as radiation dose enhancers and anticancer drug carriers.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2014/NR/C4NR02535K

Reference45 articles.

1. Nanoparticle therapeutics: an emerging treatment modality for cancer

2. Emerging implications of nanotechnology on cancer diagnostics and therapeutics

3. Shedding Light on Tumors Using Nanoparticles

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