Template-free multiple signal amplification for highly sensitive detection of cancer cell-derived exosomes-Reference-Cited by-同舟云学术

Template-free multiple signal amplification for highly sensitive detection of cancer cell-derived exosomes

Published:2021 Issue:68 Volume:57 Page:8508-8511
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Wang Lei¹,Deng Ying¹,Huang Yue²,Wei Juan³,Ma Jiehua⁴,Li Genxi¹⁵^ORCID

Affiliation:

1. State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210023, P. R. China

2. Department of Food Science and Engineering, College of Light Industry and Food Engineering, Nanjing Forestry University, Nanjing 210037, P. R. China

3. Department of Oncology, the Second Hospital of Nanjing, Nanjing University of Chinese Medicine, Nanjing 210003, P. R. China

4. The Affiliated Obstetrics and Gynecology Hospital of Nanjing Medical University (Nanjing Maternity and Child Health Care Hospital), Nanjing, China

5. Center for Molecular Recognition and Biosensing, School of Life Sciences, Shanghai University, Shanghai 200444, P. R. China

Abstract

DNase I acted as a bridge to link the DNA-based HCR and TdT-mediated polymerization. The process of DNA-involved signal amplification did not need a label or a complicated nucleic acid sequence design.

Funder

National Natural Science Foundation of China

Fundamental Research Funds for the Central Universities

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2021/CC/D1CC03640H

Reference23 articles.

1. Exosomes

2. The biology , function , and biomedical applications of exosomes

3. The Origin and Functions of Exosomes in Cancer

4. Exosomes: Extracellular organelles important in intercellular communication

5. Membrane vesicles as conveyors of immune responses

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