Stereocontrol within polyketide assembly lines-Reference-Cited by-同舟云学术

Stereocontrol within polyketide assembly lines

Published:2016 Issue:2 Volume:33 Page:141-149
ISSN:0265-0568
Container-title:Natural Product Reports
language:en
Short-container-title:Nat. Prod. Rep.

Author:

Keatinge-Clay Adrian T.¹²³⁴⁵

Affiliation:

1. Department of Molecular Biosciences

2. The University of Texas at Austin

3. Austin

4. USA

5. Department of Chemistry

Abstract

The current structural and functional data on modular polyketide synthase enzymes and their relatives has enabled the construction of physical models for how KS, KR, DH, and ER set stereocenters.

Funder

National Institutes of Health

Welch Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/NP/C5NP00092K

Reference54 articles.

1. The structures of type I polyketide synthases

2. Biosynthesis of polyketides by trans-AT polyketide synthases

3. A singular enzymatic megacomplex from Bacillus subtilis

4. The Stereochemistry of Complex Polyketide Biosynthesis by Modular Polyketide Synthases

5. antiSMASH 3.0—a comprehensive resource for the genome mining of biosynthetic gene clusters

Cited by 89 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Structure and Mechanisms of Assembly-Line Polyketide Synthases;Annual Review of Biochemistry;2024-08-02

2. Assessing and harnessing updated polyketide synthase modules through combinatorial engineering;Nature Communications;2024-08-01

3. Bioinformatic prediction of the stereoselectivity of modular polyketide synthase: an update of the sequence motifs in ketoreductase domain;Beilstein Journal of Organic Chemistry;2024-07-02

4. Discovery and Biosynthesis of Streptolateritic Acids A–D: Acyclic Pentacarboxylic Acids from Streptomyces sp. FXJ1.172 with Promising Activity against Potato Common Scab;Journal of Agricultural and Food Chemistry;2024-06-20

5. A new tetronomycin analog, broad‐spectrum and potent antibiotic against drug‐resistant Gram‐positive bacteria;Chemistry & Biodiversity;2024-02