Highly compacted pH-responsive DNA nanoparticles mediate transgene silencing in experimental glioma-Reference-Cited by-同舟云学术

Highly compacted pH-responsive DNA nanoparticles mediate transgene silencing in experimental glioma

Published:2014 Issue:46 Volume:2 Page:8165-8173
ISSN:2050-750X
Container-title:J. Mater. Chem. B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Kim Anthony J.¹²³⁴⁵,Woodworth Graeme F.¹²³⁶⁷,Boylan Nicholas J.⁶⁷³,Suk Jung Soo⁶⁷³,Hanes Justin⁶⁷³⁸⁷

Affiliation:

1. Department of Neurosurgery

2. University of Maryland School of Medicine

3. Baltimore, USA

4. Department of Pharmaceutical Sciences

5. University of Maryland School of Pharmacy

6. Center for Nanomedicine

7. Johns Hopkins University School of Medicine

8. Department of Ophthalmology, Biomedical Engineering, Chemical & Biomolecular Engineering, Neurosurgery, and Oncology

Abstract

Complex genetic mutations are common in brain cancer, making gene therapy an attractive approach to repair or modulate altered genes and cellular pathways.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2014/TB/C4TB00559G

Reference44 articles.

1. Malignant Gliomas in Adults

2. Brain Tumors in Children

3. High‐grade astrocytoma in very young children

4. Brain Tumors

5. Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma

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