Design and synthesis of 3,3′-biscoumarin-based c-Met inhibitors
Author:
Affiliation:
1. Chinese National Center for Drug Screening
2. State Key Laboratory of Drug Research
3. Shanghai Institute of Materia Medica
4. Chinese Academy of Science
5. Shanghai 201203, Republic of China
6. Division of Antitumor Pharmacology
Abstract
A series of 3,3′-biscoumarin analogues were synthesized as non-ATP competitive c-Met inhibitors.
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2014/OB/C4OB00364K
Reference35 articles.
1. Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene Product
2. MET signalling: principles and functions in development, organ regeneration and cancer
3. Drug development of MET inhibitors: targeting oncogene addiction and expedience
4. MET Amplification Leads to Gefitinib Resistance in Lung Cancer by Activating ERBB3 Signaling
5. Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion
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