Development of a polyacrylamide/chitosan composite hydrogel conduit containing synergistic cues of elasticity and topographies for promoting peripheral nerve regeneration

Author:

Liu Fang123,Xu Jiawei12,Liu Anning4,Wu Linliang12,Wang Dongzhi56,Han Qi12,Zheng Tiantian12,Wang Feiran5,Kong Yan12,Li Guicai12ORCID,Li Peng4,Gu Shouyong78,Yang Yumin123ORCID

Affiliation:

1. Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-innovation Center of Neuroregeneration, Nantong University, 226001, Nantong, P.R. China

2. NMPA Key Laboratory for Research and Evaluation of Tissue Engineering Technology Products, Nantong University, 226001, Nantong, P.R. China

3. School of Medical, Nantong University, 226001, Nantong, P.R. China

4. Department of Gastrointestinal Surgery, Affiliated Hospital of Nantong University, Nantong, Jiangsu, China, 226001

5. Department of General Surgery, Affiliated Hospital of Nantong University, Nantong, Jiangsu, China, 226001

6. Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong, Jiangsu, P.R. China, 226001

7. Geriatric Hospital affiliated to Nanjing Medical University, Nanjing, Jiangsu, P.R. China, 211166

8. Geriatric Institute of Jiangsu Province, Jiangsu, P.R. China, 211166

Abstract

The polyacrylamide/chitosan composite hydrogel containing synergistic cues of elasticity and topographies was developed by in situ free radical polymerization and micromolding methods.

Funder

National Natural Science Foundation of China

Jiangsu Provincial Department of Education

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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