Solvent-free, uncatalyzed asymmetric “ene” reactions of N-tert-butylsulfinyl-3,3,3-trifluoroacetaldimines: a general approach to enantiomerically pure α-(trifluoromethyl)tryptamines-Reference-Cited by-同舟云学术

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Solvent-free, uncatalyzed asymmetric “ene” reactions of N-tert-butylsulfinyl-3,3,3-trifluoroacetaldimines: a general approach to enantiomerically pure α-(trifluoromethyl)tryptamines

Published:2017 Issue:18 Volume:15 Page:3930-3937
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Mazzeo Giuseppe¹²³⁴,Longhi Giovanna¹²³⁴,Abbate Sergio¹²³⁴,Palomba Martina⁵⁶⁷⁴,Bagnoli Luana⁵⁶⁷⁴,Marini Francesca⁵⁶⁷⁴^ORCID,Santi Claudio⁵⁶⁷⁴,Han Jianlin⁸⁹¹⁰¹¹¹²^ORCID,Soloshonok Vadim A.¹³¹⁴¹⁵¹⁶¹⁷^ORCID,Di Crescenzo Emilio¹⁸¹⁹⁷⁴,Ruzziconi Renzo¹⁸¹⁹⁷⁴^ORCID

Affiliation:

1. Department of Molecular and Translational Medicine

2. Università di Brescia

3. 25123 Brescia

4. Italy

5. Department of Pharmaceutical Sciences

6. University of Perugia Via del Liceo 1

7. 06123 Perugia

8. School of Chemistry and Chemical Engineering

9. State Key Laboratory of Coordination Chemistry

10. Nanjing University

11. Nanjing

12. P. R. China

13. Department of Organic Chemistry I

14. Faculty of Chemistry

15. University of the Basque Country UPV/EHU

16. 20018 San Sebastián

17. Spain

18. Department of Chemistry

19. Biology and Biotechnologies

Abstract

A novel approach to stereoselectively α-trifluoromethylated tryptamines is reported.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/OB/C7OB00670E

Reference49 articles.

1. Indole Ring Synthesis: From Natural Products to Drug Discovery, ed. G. W. Gribble, John wiley & Sons, Ltd, 2016

2. Controlling bacterial behavior with indole-containing natural products and derivatives

3. Biomedical Importance of Indoles

4. Structure, Bioactivity and Synthesis of Natural Products with Hexahydropyrrolo[2,3-b]indole

5. Indoles: Industrial, Agricultural and Over-the-Counter Uses

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