Pd-catalyzed C–N coupling of vinylbromides and sulfonimidamides: a facile synthesis of N′-vinylsulfonimidamides-Reference-Cited by-同舟云学术

Pd-catalyzed C–N coupling of vinylbromides and sulfonimidamides: a facile synthesis of N′-vinylsulfonimidamides

Published:2015 Issue:76 Volume:5 Page:62084-62090
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Nandi Ganesh C.¹²³⁴⁵,Kota Sudhakar R.¹²³⁴,Wakchaure Prasad B.⁶⁷⁸⁹¹⁰,Chinthakindi Praveen K.¹²³⁴,Govender Thavendran¹²³⁴,Kruger Hendrick G.¹²³⁴,Naicker Tricia¹²³⁴,Arvidsson Per I.¹²³⁴¹¹

Affiliation:

1. Catalysis and Peptide Research Unit

2. University of KwaZulu-Natal

3. Durban

4. South Africa

5. Organic Chemistry Section

6. Organic Pharmaceutical Chemistry

7. Department of Medicinal Chemistry

8. Uppsala Biomedical Center

9. Uppsala University

10. 751 23 Uppsala

11. Science for Life Laboratory

Abstract

N′-Vinyl sulfonimidamides were synthesized through Pd-catalyzed C–N coupling; the product's utility were further demonstrated by preparing N′-alkyl sulfonimidamides through hydrogenation.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA10939F

Reference66 articles.

1. Sulfonimidamides as Sulfonamides Bioisosteres: Rational Evaluation through Synthetic, in Vitro, and in Vivo Studies with γ-Secretase Inhibitors

2. Preclinical Characterization of Acyl Sulfonimidamides: Potential Carboxylic Acid Bioisosteres with Tunable Properties

3. Synthesis and arylation of unprotected sulfonimidamides

4. Synthesis of Novel Aryl and Heteroaryl Acyl Sulfonimidamides via Pd-Catalyzed Carbonylation Using a Nongaseous Precursor

5. Synthesis of Vinyl- and Aryl-Acyl Sulfonimidamides Through Pd-Catalyzed Carbonylation Using Mo(CO)6as ex situ CO Source

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