A photo-triggerable aptamer nanoswitch for spatiotemporal controllable siRNA delivery-Reference-Cited by-同舟云学术

A photo-triggerable aptamer nanoswitch for spatiotemporal controllable siRNA delivery

Published:2020 Issue:20 Volume:12 Page:10939-10943
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Zhao Deyao¹²³⁴⁵,Yang Ge¹²³⁴⁵,Liu Qing¹²³⁴⁵,Liu Wenjing¹²³⁴⁵,Weng Yuhua¹²³⁴⁵,Zhao Yi¹²³⁴⁵,Qu Feng¹²³⁴⁵,Li Lele⁶⁷⁸⁵^ORCID,Huang Yuanyu¹²³⁴⁵^ORCID

Affiliation:

1. Advanced Research Institute of Multidisciplinary Science; School of Life Science; Institute of Engineering Medicine

2. Key Laboratory of Molecular Medicine and Biotherapy

3. Beijing Institute of Technology

4. Beijing 100081

5. China

6. CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety and CAS Center for Excellence in Nanoscience

7. National Center for Nanoscience and Technology

8. Beijing 100190

Abstract

Spatiotemporal controllable siRNA delivery and gene modulation by light-triggerable aptamer nanoswitcher was reported in this study, which achieved on-demand siRNA internalization by cancer cells at desired site and time in vitro and in vivo.

Funder

National Natural Science Foundation of China

Beijing Institute of Technology Research Fund Program for Young Scholars

Fundamental Research Funds for the Central Universities

Natural Science Foundation of Hunan Province

Huxiang Youth Talent Support Program

China Postdoctoral Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2020/NR/D0NR00301H

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5. NIR-light-mediated spatially selective triggering of anti-tumor immunity via upconversion nanoparticle-based immunodevices

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