Effective atherosclerotic plaque inflammation inhibition with targeted drug delivery by hyaluronan conjugated atorvastatin nanoparticles-Reference-Cited by-同舟云学术

Effective atherosclerotic plaque inflammation inhibition with targeted drug delivery by hyaluronan conjugated atorvastatin nanoparticles

Published:2020 Issue:17 Volume:12 Page:9541-9556
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Hossaini Nasr Seyedmehdi¹²³⁴²,Rashidijahanabad Zahra¹²³⁴²,Ramadan Sherif¹²³⁴²^ORCID,Kauffman Nate⁴²³⁵²,Parameswaran Narayanan⁶²³,Zinn Kurt R.⁴²³⁵²,Qian Chunqi⁷²³,Arora Ripla⁴²³⁸⁹,Agnew Dalen¹⁰¹¹²³,Huang Xuefei¹²³⁴²^ORCID

Affiliation:

1. Department of Chemistry Michigan State University

2. East Lansing

3. USA

4. Institute for Quantitative Health Science and Engineering Michigan State University

5. Department of Biomedical Engineering Michigan State University

6. Department of Physiology Michigan State University

7. Department of Radiology Michigan State University

8. Department of Obstetrics

9. Gynecology and Reproductive Biology Michigan State University

10. Department of Pathobiology and Diagnostic Investigation

11. Michigan State University

Abstract

Atherosclerosis is associated with inflammation in the arteries. Hyaluronan atorvastatin nanoparticle conjugate could target CD44 overexpressed in atherosclerotic plaques and significantly reduce plaque associated inflammation.

Funder

National Institute of General Medical Sciences

Michigan State University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2020/NR/D0NR00308E

Reference49 articles.

1. Atherosclerosis: current pathogenesis and therapeutic options

2. Site of intimal rupture or erosion of thrombosed coronary atherosclerotic plaques is characterized by an inflammatory process irrespective of the dominant plaque morphology.