Design, synthesis, anticonvulsant and analgesic studies of new pyrazole analogues: a Knoevenagel reaction approach-Reference-Cited by-同舟云学术

Design, synthesis, anticonvulsant and analgesic studies of new pyrazole analogues: a Knoevenagel reaction approach

Published:2015 Issue:115 Volume:5 Page:94786-94795
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Viveka Shivapura¹²³,Dinesha Dinesha¹²³,Shama Prasanna⁴⁵³,Naveen Shivalingegowda⁶⁷⁸³,Lokanath Neratur Krishnappagowda⁹⁷⁸³,Nagaraja Gundibasappa Karikannar¹²³

Affiliation:

1. Department of Studies in Chemistry

2. Mangalore University

3. India

4. Department of Pharmacology

5. N.G.S.M. Institute of Pharmaceutical Sciences

6. Institution of Excellence

7. Manasagangotri

8. University of Mysore

9. Department of Studies in Physics

Abstract

Compounds1a,4aand7a(76.58, 79.76 and 78 94% protection) shows potent anticonvulsant activity compounds1b,5a,5b,7aand7bshowed good analgesic property.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA17391D

Reference46 articles.

1. α-Fluoro-2,2,3,3-Tetramethylcyclopropanecarboxamide, a Novel Potent Anticonvulsant Derivative of a Cyclic Analogue of Valproic Acid

2. The GABA Shunt: An Attractive and Potential Therapeutic Target in the Treatment of Epileptic Disorders

3. Adverse effects of antiepileptic drugs: a brief overview of important issues

4. Molecular targets for the rational design of antiepileptic drugs and related neuroprotective agents

Cited by 40 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Therapeutic Potential of Pyrazole Containing Compounds: an Updated Review;Pharmaceutical Chemistry Journal;2024-05

2. Pyrazole appended hetero-hybrids: Bioisosteric design, synthesis, in silico and in vitro antibacterial and anti-inflammatory evaluations;Journal of Molecular Structure;2023-10

3. Potent and selective carbonic anhydrase inhibition activities of pyrazolones bearing benzenesulfonamides;Bioorganic & Medicinal Chemistry Letters;2023-10

4. (2Z,5Z)-5-((3-(Benzofuran-2-yl)-1-phenyl-1H-pyrazol-4-yl)methylene)-2-((4-methoxyphenyl)imino)-3-phenylthiazolidin-4-one;Molbank;2023-06-09

5. 5‑Sulphosalicylic acid: An expeditious Organocatalyst for one‑pot synthesis of Indenopyrazolones and its derivatives;Current Organocatalysis;2023-06-09