Nauclea latifolia: biological activity and alkaloid phytochemistry of a West African tree

Author:

Boucherle Benjamin12345,Haudecoeur Romain12345,Queiroz Emerson Ferreira678910,De Waard Michel1112134,Wolfender Jean-Luc678910,Robins Richard J.141516174,Boumendjel Ahcène12345

Affiliation:

1. Univ. Grenoble Alpes

2. DPM UMR 5063

3. F-38041 Grenoble

4. France

5. CNRS

6. School of Pharmaceutical Sciences

7. EPGL

8. University of Geneva

9. University of Lausanne

10. CH-1211 Geneva 4

11. Institut du Thorax

12. Inserm UMR 1087/CNRS UMR 6291

13. F-44007 Nantes

14. Elucidation of Biosynthesis by Isotopic Spectrometry Group

15. CEISAM Laboratory

16. University of Nantes – CNRS UMR 6230

17. F-44322 Nantes

Abstract

We review the correlation between extracted compounds fromNauclea latifoliaand their pharmacological activity, with a special focus on infectious diseases and neurological-related disorders, including analgesia. We also critically analyse the reported natural origin of tramadol extracted fromN. latifolia.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

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