Paclitaxel-loaded pluronic F127/P123 silica nanocapsules with surface conjugated rhTRAIL for targeted cancer therapy-Reference-Cited by-同舟云学术

Paclitaxel-loaded pluronic F127/P123 silica nanocapsules with surface conjugated rhTRAIL for targeted cancer therapy

Published:2017 Issue:48 Volume:7 Page:30250-30261
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Liu Xin¹²³⁴⁵^ORCID,Li Yuebin⁶⁷⁸³⁴,He Jian⁶⁷⁸³⁴^ORCID,Zhao Tingting⁶⁷⁸³⁴^ORCID,Chen Changmei¹²³⁴⁵^ORCID,Gu Haoshuang⁶⁷⁸³⁴,Wang Xingguo¹²³⁴⁵^ORCID

Affiliation:

1. Hubei Collaborative Innovation Center for Green Transformation of Bioresources

2. The Faculty of Life Science

3. Hubei University

4. Wuhan 430062

5. China

6. Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials

7. Hubei Key Laboratory of Ferro & Piezoelectric Materials and Devices

8. Faculty of Physics & Electronic Sciences

Abstract

A novel anticancer drug PFPSNT, paclitaxel (PTX)-loaded polymeric F127/P123 silica nanocapsules conjugated with TRAIL (tumor necrosis factor (TNF)-related apoptosis-inducing ligand), was designed and synthesized.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/RA/C7RA04503D

Reference52 articles.

1. The Receptor for the Cytotoxic Ligand TRAIL

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3. Differential cleavage of Mst1 by caspase-7/-3 is responsible for TRAIL-induced activation of the MAPK superfamily

4. Phase I Dose-Escalation Study of Recombinant Human Apo2L/TRAIL, a Dual Proapoptotic Receptor Agonist, in Patients With Advanced Cancer

5. Phase 1b Study of Dulanermin (recombinant human Apo2L/TRAIL) in Combination With Paclitaxel, Carboplatin, and Bevacizumab in Patients With Advanced Non-Squamous Non–Small-Cell Lung Cancer

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