Innovative omics-based approaches for prioritisation and targeted isolation of natural products – new strategies for drug discovery
Author:
Affiliation:
1. School of Pharmaceutical Sciences
2. University of Geneva
3. University of Lausanne
4. 1211 Geneva 11
5. Switzerland
6. Institut de Chimie des Substances Naturelles
7. CNRS-ICSN
8. UPR 2301
9. Université Paris-Saclay
10. Gif-sur-Yvette
Abstract
This review focuses on innovative omics approaches related to the prioritisation of natural extracts, to selection of efficient producing strains and to the targeted isolation of their bioactive constituents.
Funder
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2019/NP/C9NP00004F
Reference72 articles.
1. Plant natural products: Back to the future or into extinction?
2. The pharmaceutical industry and natural products: historical status and new trends
3. New regulations for accessing plant biodiversity samples, what is ABS?
4. Accelerating Metabolite Identification in Natural Product Research: Toward an Ideal Combination of Liquid Chromatography–High-Resolution Tandem Mass Spectrometry and NMR Profiling, in Silico Databases, and Chemometrics
5. E. Maréchal , S.Roy and L.Lafanechère , Chemogenomics and Chemical Genetics , Springer-Verlag , Berlin, Heidelberg , 2011
Cited by 128 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Molecular networking unveils anti-SARS-CoV-2 constituents from traditionally used remedies;Journal of Ethnopharmacology;2024-01
2. Spatialized Metabolomic Annotation Combining MALDI Imaging and Molecular Networks;Analytical Chemistry;2023-12-22
3. Artificial intelligence: Machine learning approach for screening large database and drug discovery;Antiviral Research;2023-12
4. Capsiate-Rich Fraction of Capsicum annuum Induces Muscular Glucose Uptake, Ameliorates Rosiglitazone-Induced Adipogenesis, and Exhibits Activation of NRs Regulating Multiple Signaling Pathways;Journal of Agricultural and Food Chemistry;2023-11-16
5. Bioprospecting-based untargeted metabolomics identifies alkaloids as potential anti-inflammatory bioactive markers of Ocotea species (Lauraceae);Phytomedicine;2023-11
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3