Evaluation of antiviral activity of <i>Carica papaya</i> leaves against SARS-CoV-2 assisted by metabolomic profiling-Reference-Cited by-同舟云学术

Evaluation of antiviral activity of Carica papaya leaves against SARS-CoV-2 assisted by metabolomic profiling

Published:2022 Issue:51 Volume:12 Page:32844-32852
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Adel Amr¹^ORCID,Elnaggar Mohamed S.²^ORCID,Albohy Amgad³^ORCID,Elrashedy Ahmed A.⁴,Mostafa Ahmed⁵^ORCID,Kutkat Omnia⁵,Abdelmohsen Usama Ramadan⁶⁷^ORCID,Al-Sayed Eman²^ORCID,Rabeh Mohamed A.¹⁸

Affiliation:

1. Department of Pharmacognosy, Faculty of Pharmacy, Modern University for Technology and Information, 11865, Cairo, Egypt

2. Department of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, 11566, Cairo, Egypt

3. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, The British University in Egypt (BUE), Suez Desert Road, ElSherouk City, 11837, Cairo, Egypt

4. Natural and Microbial Chemistry Department, Pharmaceutical and Drug Industries Research Division, National Research Centre (NRC), AlBohoos Street, Dokki, 12311, Cairo, Egypt

5. Center of Scientific Excellence for Influenza Viruses, National Research Centre, 12622, Giza, Egypt

6. Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia, 61519, Egypt

7. Department of Pharmacognosy, Faculty of Pharmacy, Deraya University, Minia, 61111, Egypt

8. Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, 11562, Giza, Egypt

Abstract

The n-hexane extract showed a significant antiviral activity. In addition, annotated compounds exhibited high binding scores on 6 target viral proteins in silico.

Funder

Academy of Scientific Research and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/RA/D2RA04600H

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4. Anti-inflammatory activities of ethanolic extract of Carica papaya leaves

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