In vitro biocatalytic pathway design: orthogonal network for the quantitative and stereospecific amination of alcohols

Author:

Knaus Tanja1234ORCID,Cariati Luca1234ORCID,Masman Marcelo F.1234ORCID,Mutti Francesco G.1234ORCID

Affiliation:

1. Van't Hoff Institute for Molecular Sciences

2. HIMS-Biocat

3. University of Amsterdam

4. The Netherlands

Abstract

An artificial, orthogonal, biocatalytic network converts alcohols quantitatively into enantiopure amines, consuming ammonia and dioxygen and generating carbonate as by-product.

Funder

H2020 European Research Council

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Reference75 articles.

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2. Chiral amine synthesis: Methods, Developments and Applications, ed. T. C. Nugent, Wiley-VCH, Weinheim, 2010

3. S. K. Au , J.Groover, B. D.Feske and A. S.Bommarius, in Organic Synthesis Using Biocatalysis, Elsevier, 1st edn, 2015, pp. 187–212

4. A Simple Conversion of Alcohols into Amines

5. Mitsunobu and Related Reactions: Advances and Applications

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