Synthesis and anticancer cytotoxicity with structural context of an α-hydroxyphosphonate based compound library derived from substituted benzaldehydes-Reference-Cited by-同舟云学术

Synthesis and anticancer cytotoxicity with structural context of an α-hydroxyphosphonate based compound library derived from substituted benzaldehydes

Published:2019 Issue:35 Volume:43 Page:14028-14035
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Rádai Zita¹²³⁴^ORCID,Windt Tímea⁵⁶⁷³⁴^ORCID,Nagy Veronika⁵⁶⁷³⁴,Füredi András⁵⁶⁷³⁴^ORCID,Kiss Nóra Zsuzsa¹²³⁴^ORCID,Ranđelović Ivan⁸⁹³⁴¹⁰^ORCID,Tóvári József⁸⁹³⁴¹⁰,Keglevich György¹²³⁴^ORCID,Szakács Gergely⁵⁶⁷³⁴^ORCID,Tóth Szilárd⁵⁶⁷³⁴^ORCID

Affiliation:

1. Department of Organic Chemistry and Technology

2. Budapest University of Technology and Economics

3. Budapest

4. Hungary

5. Institute of Enzymology

6. Research Centre for Natural Sciences

7. Hungarian Academy of Sciences

8. National Institute of Oncology

9. Department of Experimental Pharmacology

10. Kineto Lab Ltd

Abstract

We synthesized substituted benzaldehyde derived α-hydroxyphosphonates (αOHP), α-hydroxyphosphonic acids (αOHPA) and α-phosphinoyloxyphosphonates (αOPP) and characterized their cytotoxicity against a panel of cancer cell lines.

Funder

Magyar Tudományos Akadémia

Nemzeti Kutatási, Fejlesztési és Innovaciós Alap

Nemzeti Kutatási Fejlesztési és Innovációs Hivatal

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2019/NJ/C9NJ02144B

Reference32 articles.

1. Synthesis and Reactions of α-Hydroxyphosphonates